| Gene Information | |
|---|---|
| Gene Name | PDE1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 535 |
| Protein Names | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Cam-PDE 1A) (EC 3.1.4.17) (61 kDa Cam-PDE) (hCam-1) |
| Target Name | cyclic nucleotide phosphodiesterase |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000115252 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P54750 |
| Gene Card | PDE1A |
| Uniprot ID | P54750 |
| Pfam | PF00233; PF08499 |
| In ASD | no |
| Allosteric Prediction | yes (1.132704314) |
| Ortholog in Animals | Alpaca_ PDE1A ( ortholog_one2one ) Dog_ PDE1A ( ortholog_one2one ) GuineaPig_ PDE1A ( ortholog_one2one ) Macaque_ PDE1A ( ortholog_one2one ) Mouse_ Pde1a ( ortholog_one2one ) Pig_ PDE1A ( ortholog_one2one ) Rat_ Pde1a ( ortholog_one2one ) Rabbit_ PDE1A ( ortholog_one2one ) |
| Ohnologs | PDE1B, PDE1C |
| Paralogs | PDE8A, PDE4A, PDE4D, PDE4B, PDE6A, PDE2A, PDE6C, PDE8B, PDE1B, PDE9A, PDE10A, PDE7A, PDE3B, PDE1C, PDE11A, PDE5A, PDE3A, PDE7B, PDE6B, PDE4C |
| Tissue | NA |
| Tissue Specificity | Several tissues, including brain, kidney, testes and heart. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.085714(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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