| Gene Information | |
|---|---|
| Gene Name | PEA15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 130 |
| Protein Names | Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes) (Phosphoprotein enriched in diabetes) (PED) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000162734 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15121 |
| Gene Card | PEA15 |
| Uniprot ID | Q15121 |
| Pfam | PF01335 |
| In ASD | no |
| Allosteric Prediction | no (-0.320650192) |
| Ortholog in Animals | Alpaca_ PEA15 ( ortholog_one2one ) Dog_ PEA15 ( ortholog_one2one ) GuineaPig_ PEA15 ( ortholog_one2one ) Macaque_ PEA15 ( ortholog_one2one ) Mouse_ Pea15a ( ortholog_one2one ) Pig_ PEA15 ( ortholog_one2one ) Rat_ Pea15 ( ortholog_one2one ) Rabbit_ PEA15 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls. {ECO:0000269|PubMed:9670003}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4IZ5 (X-ray 3.19A ) 4IZA (X-ray 1.93A ) 6P6B (NMR - ) 6P6C (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Note=Associated with microtubules. |
| Mouse PG classification | NA |
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