| Gene Information | |
|---|---|
| Gene Name | ARHGDIA |
| Organism | Homo sapiens (Human) |
| Gene Length | 204 |
| Protein Names | Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000141522 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P52565 |
| Gene Card | ARHGDIA |
| Uniprot ID | P52565 |
| Pfam | PF02115 |
| In ASD | yes |
| Allosteric Prediction | yes (0.537443184) |
| Ortholog in Animals | Alpaca_ ARHGDIA ( ortholog_one2one ) Dog_ ARHGDIA ( ortholog_one2one ) GuineaPig_ ARHGDIA ( ortholog_one2one ) Macaque_ ARHGDIA ( ortholog_one2one ) Mouse_ Arhgdia ( ortholog_one2one ) Pig_ ARHGDIA ( ortholog_one2one ) Rat_ Arhgdia ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARHGDIB, ARHGDIG |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001546(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CC0 (X-ray 5.00A ) 1FSO (X-ray 2.00A ) 1FST (X-ray 2.70A ) 1FT0 (X-ray 2.60A ) 1FT3 (X-ray 2.80A ) 1HH4 (X-ray 2.70A ) 1KMT (X-ray 1.30A ) 1QVY (X-ray 1.60A ) 1RHO (X-ray 2.50A ) 2BXW (X-ray 2.40A ) 2JHS (X-ray 1.95A ) 2JHT (X-ray 1.88A ) 2JHU (X-ray 1.65A ) 2JHV (X-ray 2.07A ) 2JHW (X-ray 2.50A ) 2JHX (X-ray 1.60A ) 2JHY (X-ray 1.90A ) 2JHZ (X-ray 2.20A ) 2JI0 (X-ray 2.10A ) 2N80 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23434736}. |
| Mouse PG classification | NA |
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