| Gene Information | |
|---|---|
| Gene Name | HSPA1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 641 |
| Protein Names | Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000204388 ) 3 ( ENSG00000212866 ) 3 ( ENSG00000224501 ) 3 ( ENSG00000231555 ) 3 ( ENSG00000232804 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P0DMV9 |
| Gene Card | HSPA1B |
| Uniprot ID | P0DMV9 |
| Pfam | PF00012 |
| In ASD | no |
| Allosteric Prediction | yes (0.998321544) |
| Ortholog in Animals | Dog_ HSP70 ( ortholog_one2many ) Mouse_ Hspa1a ( ortholog_many2many ) Mouse_ Hspa1b ( ortholog_many2many ) |
| Ohnologs | HSPA8, HSPA2 |
| Paralogs | HSPA4L, HSPA6, HSPA1L, HSPH1, HSPA2, HSPA9, HSPA13, HSPA5, HSPA14, HSPA8, HYOU1, HSPA4, HSPA1A |
| Tissue | NA |
| Tissue Specificity | HSPA1B is testis-specific. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.021053(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4J8F (X-ray 2.70A ) 6FDT (NMR - ) 7F4X (Other 1.60A ) 7F4Z (X-ray 1.80A ) 7F50 (X-ray 1.70A ) |
| DBSNP | rs538280104 rs483638 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17289661}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:27137183}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
| Mouse PG classification | NA |
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