| Gene Information | |
|---|---|
| Gene Name | PDXK |
| Organism | Homo sapiens (Human) |
| Gene Length | 312 |
| Protein Names | Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) |
| Target Name | pyridoxal kinase |
| Target Type | Literature-reported target |
| Gene Age | 987 ( ENSG00000160209 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O00764 |
| Gene Card | PDXK |
| Uniprot ID | O00764 |
| Pfam | PF08543 |
| In ASD | no |
| Allosteric Prediction | yes (0.374492289) |
| Ortholog in Animals | Alpaca_ PDXK ( ortholog_one2one ) GuineaPig_ PDXK ( ortholog_one2one ) Macaque_ PDXK ( ortholog_one2one ) Mouse_ Pdxk ( ortholog_one2one ) Pig_ PDXK ( ortholog_one2one ) Rat_ Pdxk ( ortholog_one2many ) Rat_ RGD1566085 ( ortholog_one2many ) Rabbit_ PDXK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | Ubiquitous (PubMed:9099727, PubMed:31187503). Highly expressed in testis (PubMed:9099727). {ECO:0000269|PubMed:31187503, ECO:0000269|PubMed:9099727}.; [Isoform 3]: In adult testis and spermatozoa. {ECO:0000269|PubMed:15154080}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2AJP (X-ray 2.50A ) 2F7K (X-ray 2.80A ) 2YXT (X-ray 2.00A ) 2YXU (X-ray 2.20A ) 3FHX (X-ray 2.50A ) 3FHY (X-ray 2.30A ) 3KEU (X-ray 2.10A ) 4EN4 (X-ray 2.15A ) 4EOH (X-ray 2.10A ) |
| DBSNP | rs759333796 rs757480516 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:9099727}. |
| Mouse PG classification | NA |
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