| Gene Information | |
|---|---|
| Gene Name | GAD65 |
| Organism | Homo sapiens (Human) |
| Gene Length | 585 |
| Protein Names | Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform) |
| Target Name | glutamic acid decarboxylase |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q05329 |
| Gene Card | GAD2 |
| Uniprot ID | Q05329 |
| Pfam | PF00282 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ES0 (X-ray 2.60A ) 2OKK (X-ray 2.30A ) |
| DBSNP | rs8190591 rs8190600 rs2839672 rs2839673 rs8190671 rs2839678 rs8190730 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:12356867}. Cytoplasmic vesicle {ECO:0000269|PubMed:12356867}. Presynaptic cell membrane {ECO:0000269|PubMed:12356867}; Lipid-anchor {ECO:0000269|PubMed:12356867}. Golgi apparatus membrane {ECO:0000269|PubMed:12356867}; Peripheral membrane protein {ECO:0000269|PubMed:12356867}; Cytoplasmic side {ECO:0000269|PubMed:12356867}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters. |
| Mouse PG classification | NA |
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