| Gene Information | |
|---|---|
| Gene Name | PDLIM7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 457 |
| Protein Names | PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000196923 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9NR12 |
| Gene Card | PDLIM7 |
| Uniprot ID | Q9NR12 |
| Pfam | PF00412; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.220263723) |
| Ortholog in Animals | Alpaca_ PDLIM7 ( ortholog_one2one ) GuineaPig_ PDLIM7 ( ortholog_one2one ) Macaque_ PDLIM7 ( ortholog_one2one ) Mouse_ Pdlim7 ( ortholog_one2one ) Pig_ PDLIM7 ( ortholog_one2one ) Rat_ Pdlim7 ( ortholog_one2one ) |
| Ohnologs | LDB3, PDLIM5 |
| Paralogs | PDLIM2, PDLIM1, PDLIM3, LDB3, PDLIM5, PDLIM4, PRICKLE4 |
| Tissue | penis, smooth.muscle |
| Tissue Specificity | Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver. {ECO:0000269|PubMed:11874232}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2Q3G (X-ray 1.11A ) 7RM8 (NMR - ) |
| DBSNP | rs2306764 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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