| Gene Information | |
|---|---|
| Gene Name | RFX4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 735 |
| Protein Names | Transcription factor RFX4 (Regulatory factor X 4) (Testis development protein NYD-SP10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000111783 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q33E94 |
| Gene Card | RFX4 |
| Uniprot ID | Q33E94 |
| Pfam | PF02257 |
| In ASD | no |
| Allosteric Prediction | no (-1.06729641) |
| Ortholog in Animals | Alpaca_ RFX4 ( ortholog_one2one ) Dog_ RFX4 ( ortholog_one2one ) GuineaPig_ RFX4 ( ortholog_one2one ) Macaque_ RFX4 ( ortholog_one2one ) Mouse_ Rfx4 ( ortholog_one2one ) Pig_ RFX4 ( ortholog_one2one ) Rat_ Rfx4 ( ortholog_one2one ) Rabbit_ RFX4 ( ortholog_one2one ) |
| Ohnologs | RFX6 |
| Paralogs | RFX7, RFX5, RFX6, RFX8, RFX2, RFX3, RFX1 |
| Tissue | testis |
| Tissue Specificity | Isoform 1: Expressed in brain and gliomas (at protein level). Isoform 2: Testis-specific (at protein level). Isoform 3: Testis-specific (at protein level). Isoform 3: Expressed at a higher level in adult testes and ejaculated spermatozoa than in fetal testes. Isoform 4: Testis-specific. {ECO:0000269|PubMed:11682486, ECO:0000269|PubMed:16193984, ECO:0000269|PubMed:16271074}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17038766 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00858}. |
| Mouse PG classification | NA |
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