| Gene Information | |
|---|---|
| Gene Name | PDIA5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 519 |
| Protein Names | Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000065485 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14554 |
| Gene Card | PDIA5 |
| Uniprot ID | Q14554 |
| Pfam | PF00085 |
| In ASD | yes |
| Allosteric Prediction | no (-0.145991069) |
| Ortholog in Animals | Alpaca_ PDIA5 ( ortholog_one2one ) Dog_ PDIA5 ( ortholog_one2one ) GuineaPig_ PDIA5 ( ortholog_one2one ) Macaque_ PDIA5 ( ortholog_one2one ) Mouse_ Pdia5 ( ortholog_one2one ) Pig_ PDIA5 ( ortholog_one2one ) Rat_ Pdia5 ( ortholog_one2one ) Rabbit_ PDIA5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ERP27, PDIA6, TMX1, TXNDC11, TMX4, TMX3, PDILT, ERP44, PDIA2, PDIA3, PDIA4, P4HB, TXNDC5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4I6X (X-ray 1.50A ) |
| DBSNP | rs2292661 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. |
| Mouse PG classification | NA |
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