| Gene Information | |
|---|---|
| Gene Name | ECSCR |
| Organism | Homo sapiens (Human) |
| Gene Length | 205 |
| Protein Names | Endothelial cell-specific chemotaxis regulator (Apoptosis regulator through modulating IAP expression) (ARIA) (Endothelial cell-specific molecule 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000249751 ) 3 ( ENSG00000288297 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q19T08 |
| Gene Card | ECSCR |
| Uniprot ID | Q19T08 |
| Pfam | PF15820 |
| In ASD | no |
| Allosteric Prediction | no (-0.99997259) |
| Ortholog in Animals | Alpaca_ ECSCR ( ortholog_one2one ) Mouse_ Ecscr ( ortholog_one2one ) Pig_ ECSCR ( ortholog_one2one ) Rat_ Ecscr ( ortholog_one2one ) Rabbit_ ECSCR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells. {ECO:0000269|PubMed:18556573, ECO:0000269|PubMed:19416853}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Cytoplasm. |
| Mouse PG classification | NA |
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