| Gene Information | |
|---|---|
| Gene Name | PDGFA |
| Organism | Homo sapiens (Human) |
| Gene Length | 211 |
| Protein Names | Platelet-derived growth factor subunit A (PDGF subunit A) (PDGF-1) (Platelet-derived growth factor A chain) (Platelet-derived growth factor alpha polypeptide) |
| Target Name | platelet-derived growth factor a |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000197461 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P04085 |
| Gene Card | PDGFA |
| Uniprot ID | P04085 |
| Pfam | PF00341; PF04692 |
| In ASD | no |
| Allosteric Prediction | no (-0.180209808) |
| Ortholog in Animals | Dog_ PDGFA ( ortholog_one2one ) GuineaPig_ PDGFA ( ortholog_one2one ) Macaque_ PDGFA ( ortholog_one2one ) Mouse_ Pdgfa ( ortholog_one2one ) Pig_ PDGFA ( ortholog_one2one ) Rat_ Pdgfa ( ortholog_one2one ) Rabbit_ PDGFA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PDGFB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MJK (X-ray 2.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. Note=Released by platelets upon wounding. |
| Mouse PG classification | NA |
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