| Gene Information | |
|---|---|
| Gene Name | MOG |
| Organism | Homo sapiens (Human) |
| Gene Length | 247 |
| Protein Names | Myelin-oligodendrocyte glycoprotein |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000137345 ) 544 ( ENSG00000204655 ) 3 ( ENSG00000230885 ) 3 ( ENSG00000232641 ) 3 ( ENSG00000234096 ) 3 ( ENSG00000234623 ) 3 ( ENSG00000236561 ) 3 ( ENSG00000237834 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q16653 |
| Gene Card | MOG |
| Uniprot ID | Q16653 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.431330972) |
| Ortholog in Animals | Alpaca_ MOG ( ortholog_one2one ) Dog_ MOG ( ortholog_one2one ) GuineaPig_ MOG ( ortholog_one2one ) Macaque_ MOG ( ortholog_one2one ) Mouse_ Mog ( ortholog_one2one ) Pig_ MOG ( ortholog_one2one ) Rat_ Mog ( ortholog_one2one ) Rabbit_ MOG ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BTN2A2, CD276, BTNL2, BTN2A1, BTNL9, ICOSLG, ERMAP, HHLA2, VTCN1, BTN1A1, BTN3A3, BTN3A2, BTN3A1, BTNL3, BTNL8 |
| Tissue | brain, cerebral.cortex, hippocampus, putamen, substantia.nigra |
| Tissue Specificity | Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs387906655 rs2857766 rs3130253 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.; [Isoform 5]: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.; [Isoform 2]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 3]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 4]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 6]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 7]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 8]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 9]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | LPG |
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