| Gene Information | |
|---|---|
| Gene Name | GCN5L2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 837 |
| Protein Names | Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92830 |
| Gene Card | KAT2A |
| Uniprot ID | Q92830 |
| Pfam | PF00583; PF00439; PF06466 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested. {ECO:0000269|PubMed:8684459}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.087684(Rat);0.070670(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1F68 (NMR - ) 1Z4R (X-ray 1.74A ) 3D7C (X-ray 2.06A ) 5H84 (X-ray 2.00A ) 5H86 (X-ray 2.08A ) 5MLJ (X-ray 1.80A ) 5TRL (X-ray 2.30A ) 5TRM (X-ray 2.90A ) 6J3P (X-ray 1.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11564863, ECO:0000269|PubMed:27796307, ECO:0000269|PubMed:29211711}. Chromosome {ECO:0000269|PubMed:29211711}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:27796307}. Note=Mainly localizes to the nucleus (PubMed:27796307). Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation (PubMed:27796307). {ECO:0000269|PubMed:27796307}. |
| Mouse PG classification | NA |
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