| Gene Information | |
|---|---|
| Gene Name | PDE1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 536 |
| Protein Names | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (EC 3.1.4.17) (63 kDa Cam-PDE) |
| Target Name | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1b |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000123360 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q01064 |
| Gene Card | PDE1B |
| Uniprot ID | Q01064 |
| Pfam | PF00233; PF08499 |
| In ASD | no |
| Allosteric Prediction | yes (1.087258718) |
| Ortholog in Animals | Alpaca_ PDE1B ( ortholog_one2one ) Dog_ PDE1B ( ortholog_one2one ) GuineaPig_ PDE1B ( ortholog_one2one ) Macaque_ PDE1B ( ortholog_one2one ) Mouse_ Pde1b ( ortholog_one2one ) Pig_ PDE1B ( ortholog_one2one ) Rat_ Pde1b ( ortholog_one2one ) Rabbit_ PDE1B ( ortholog_one2one ) |
| Ohnologs | PDE1A, PDE1C |
| Paralogs | PDE8A, PDE4A, PDE4D, PDE4B, PDE6A, PDE2A, PDE6C, PDE8B, PDE9A, PDE10A, PDE1A, PDE7A, PDE3B, PDE1C, PDE11A, PDE5A, PDE3A, PDE7B, PDE6B, PDE4C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TAZ (X-ray 1.77A ) 4NPV (X-ray 2.40A ) 4NPW (X-ray 1.90A ) 5B25 (X-ray 1.90A ) 5UOY (X-ray 1.82A ) 5UP0 (X-ray 2.04A ) 5W6E (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:8855339}. |
| Mouse PG classification | NA |
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