| Gene Information | |
|---|---|
| Gene Name | SLC8B1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 584 |
| Protein Names | Mitochondrial sodium/calcium exchanger protein (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Sodium/potassium/calcium exchanger 6) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000089060 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6J4K2 |
| Gene Card | SLC8B1 |
| Uniprot ID | Q6J4K2 |
| Pfam | PF01699 |
| In ASD | no |
| Allosteric Prediction | no (-0.488451638) |
| Ortholog in Animals | Alpaca_ SLC8B1 ( ortholog_one2one ) Dog_ SLC8B1 ( ortholog_one2one ) GuineaPig_ SLC8B1 ( ortholog_one2one ) Macaque_ SLC8B1 ( ortholog_one2one ) Mouse_ Slc8b1 ( ortholog_one2one ) Pig_ SLC8B1 ( ortholog_one2one ) Rat_ Slc8b1 ( ortholog_one2one ) Rabbit_ SLC8B1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Present in pancreatic beta-cells (at protein level). {ECO:0000269|PubMed:23056385}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16942745 rs3764034 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:20018762, ECO:0000269|PubMed:23056385}; Multi-pass membrane protein {ECO:0000269|PubMed:20018762, ECO:0000269|PubMed:23056385}. |
| Mouse PG classification | NA |
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