| Gene Information | |
|---|---|
| Gene Name | ENC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 589 |
| Protein Names | Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000171617 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14682 |
| Gene Card | ENC1 |
| Uniprot ID | O14682 |
| Pfam | PF07707; PF00651; PF01344 |
| In ASD | no |
| Allosteric Prediction | no (-0.951816783) |
| Ortholog in Animals | Alpaca_ ENC1 ( ortholog_one2one ) Dog_ ENC1 ( ortholog_one2one ) GuineaPig_ ENC1 ( ortholog_one2one ) Macaque_ ENC1 ( ortholog_one2one ) Mouse_ Enc1 ( ortholog_one2one ) Pig_ ENC1 ( ortholog_one2one ) Rat_ Enc1 ( ortholog_one2one ) Rabbit_ ENC1 ( ortholog_one2one ) |
| Ohnologs | KLHL25 |
| Paralogs | KLHL25, BTBD17 |
| Tissue | NA |
| Tissue Specificity | Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. May be down-regulated in neuroblastoma tumors. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16872126 |
| Subcellular location [CC] | Nucleus matrix {ECO:0000269|PubMed:19424503}. Cytoplasm {ECO:0000269|PubMed:19424503}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19424503}. |
| Mouse PG classification | NA |
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