| Gene Information | |
|---|---|
| Gene Name | CYP2W1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 490 |
| Protein Names | Cytochrome P450 2W1 (EC 1.14.14.-) (CYPIIW1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000073067 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TAV3 |
| Gene Card | CYP2W1 |
| Uniprot ID | Q8TAV3 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | no (-1.040013138) |
| Ortholog in Animals | Alpaca_ CYP2W1 ( ortholog_one2one ) Dog_ CYP2W1 ( ortholog_one2one ) GuineaPig_ CYP2W1 ( ortholog_one2one ) Macaque_ CYP2W1 ( ortholog_one2one ) Mouse_ Cyp2w1 ( ortholog_one2one ) Pig_ CYP2W1 ( ortholog_one2one ) Rat_ Cyp2w1 ( ortholog_one2one ) |
| Ohnologs | CYP2S1 |
| Paralogs | CYP2S1, CYP2D6, CYP2C18, CYP2C9, CYP2C19, CYP2B6, CYP2C8, CYP2U1, CYP2A6, CYP2A7, CYP2A13, CYP2F1, CYP2R1, CYP2E1, CYP2J2 |
| Tissue | adrenal.gland, suprapubic.skin |
| Tissue Specificity | Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors. {ECO:0000269|PubMed:16426568}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1316523256 rs3735684 rs78873069 rs773499447 rs3808348 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000269|PubMed:20805301}. Cell membrane {ECO:0000269|PubMed:20805301}. Microsome membrane {ECO:0000269|PubMed:20805301}. Note=About 8% are expressed on the cell surface. {ECO:0000269|PubMed:20805301}. |
| Mouse PG classification | NA |
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