| Gene Information | |
|---|---|
| Gene Name | PCYT1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 369 |
| Protein Names | Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B) |
| Target Name | choline-phosphate cytidylyltransferase b |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000102230 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y5K3 |
| Gene Card | PCYT1B |
| Uniprot ID | Q9Y5K3 |
| Pfam | PF01467 |
| In ASD | no |
| Allosteric Prediction | yes (0.211091356) |
| Ortholog in Animals | Alpaca_ PCYT1B ( ortholog_one2one ) Dog_ PCYT1B ( ortholog_one2one ) GuineaPig_ PCYT1B ( ortholog_one2one ) Macaque_ PCYT1B ( ortholog_one2one ) Mouse_ Pcyt1b ( ortholog_one2one ) Pig_ PCYT1B ( ortholog_one2one ) Rat_ Pcyt1b ( ortholog_one2one ) Rabbit_ PCYT1B ( ortholog_one2one ) |
| Ohnologs | PCYT1A |
| Paralogs | PCYT1A, PCYT2 |
| Tissue | brain, testis |
| Tissue Specificity | [Isoform 1]: Highly expressed in testis, placenta, brain, ovary, liver and fetal lung. {ECO:0000269|PubMed:10480912, ECO:0000269|PubMed:9593753}.; [Isoform 2]: Expressed in brain, liver and fetal lung. {ECO:0000269|PubMed:10480912}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:9593753}. Endoplasmic reticulum {ECO:0000269|PubMed:10480912}.; [Isoform 2]: Endoplasmic reticulum {ECO:0000269|PubMed:10480912}. |
| Mouse PG classification | NA |
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