| Gene Information | |
|---|---|
| Gene Name | PCTP |
| Organism | Homo sapiens (Human) |
| Gene Length | 214 |
| Protein Names | Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2) |
| Target Name | phosphatidylcholine transfer protein |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000141179 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9UKL6 |
| Gene Card | PCTP |
| Uniprot ID | Q9UKL6 |
| Pfam | PF01852 |
| In ASD | no |
| Allosteric Prediction | no (-0.634628964) |
| Ortholog in Animals | Alpaca_ PCTP ( ortholog_one2one ) GuineaPig_ PCTP ( ortholog_one2one ) Macaque_ PCTP ( ortholog_one2one ) Mouse_ Pctp ( ortholog_one2one ) Rat_ Pctp ( ortholog_one2one ) Rabbit_ PCTP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | STARD7, STARD10 |
| Tissue | NA |
| Tissue Specificity | Highest expression in liver, placenta, testis, kidney and heart. Low levels in brain and lung. No expression detected in thymus. {ECO:0000269|PubMed:10542325}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1LN1 (X-ray 2.40A ) 1LN2 (X-ray 2.90A ) 1LN3 (X-ray 2.90A ) |
| DBSNP | rs12941739 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P53808}. |
| Mouse PG classification | NA |
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