| Gene Information | |
|---|---|
| Gene Name | SRGAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1085 |
| Protein Names | SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000196935 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z6B7 |
| Gene Card | SRGAP1 |
| Uniprot ID | Q7Z6B7 |
| Pfam | PF00611; PF00620; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.866140041) |
| Ortholog in Animals | Alpaca_ SRGAP1 ( ortholog_one2one ) Dog_ SRGAP1 ( ortholog_one2one ) GuineaPig_ SRGAP1 ( ortholog_one2one ) Macaque_ SRGAP1 ( ortholog_one2one ) Mouse_ Srgap1 ( ortholog_one2one ) Pig_ SRGAP1 ( ortholog_one2one ) Rat_ Srgap1 ( ortholog_one2one ) Rabbit_ SRGAP1 ( ortholog_one2one ) |
| Ohnologs | ARHGAP4, SRGAP3 |
| Paralogs | SRGAP2B, SRGAP2, SRGAP2C, SRGAP3, ARHGAP4 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, lung, kidney, and testis. {ECO:0000269|PubMed:11672528}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs781626187 rs797044990 rs74691643 rs114817817 rs61754221 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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