| Gene Information | |
|---|---|
| Gene Name | PCOLCE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 415 |
| Protein Names | Procollagen C-endopeptidase enhancer 2 (Procollagen COOH-terminal proteinase enhancer 2) (PCPE-2) (Procollagen C-proteinase enhancer 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163710 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UKZ9 |
| Gene Card | PCOLCE2 |
| Uniprot ID | Q9UKZ9 |
| Pfam | PF00431; PF01759 |
| In ASD | no |
| Allosteric Prediction | no (-0.642724702) |
| Ortholog in Animals | Alpaca_ PCOLCE2 ( ortholog_one2one ) Dog_ PCOLCE2 ( ortholog_one2one ) GuineaPig_ PCOLCE2 ( ortholog_one2one ) Macaque_ PCOLCE2 ( ortholog_one2one ) Mouse_ Pcolce2 ( ortholog_one2one ) Pig_ PCOLCE2 ( ortholog_one2one ) Rat_ PCOLCE2 ( ortholog_one2one ) Rabbit_ PCOLCE2 ( ortholog_one2one ) |
| Ohnologs | PCOLCE |
| Paralogs | CNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, MEP1A, NRXN2, CNTNAP2, MFRP, CUZD1, NETO2, TLL2, F5, PCOLCE, CP, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, NRP2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the heart, trabecular meshwork, pituitary gland, bladder, mammary gland, trachea and placenta and weakly expressed in the brain. Expressed in cartilage. {ECO:0000269|PubMed:10873381, ECO:0000269|PubMed:11597177, ECO:0000269|PubMed:12393877}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35692900 rs17554211 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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