| Gene Information | |
|---|---|
| Gene Name | PCOLC |
| Organism | Homo sapiens (Human) |
| Gene Length | 986 |
| Protein Names | Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P13497 |
| Gene Card | BMP1 |
| Uniprot ID | P13497 |
| Pfam | PF01400; PF00431; PF07645 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EDG (X-ray 1.27A ) 3EDH (X-ray 1.25A ) 6BSL (X-ray 1.45A ) 6BSM (X-ray 2.33A ) 6BTN (X-ray 2.05A ) 6BTO (X-ray 2.05A ) 6BTP (X-ray 1.93A ) 6BTQ (X-ray 1.75A ) |
| DBSNP | rs318240762 rs398122891 rs786205219 rs11996036 |
| Subcellular location [CC] | Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:12637569}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12637569}. Secreted {ECO:0000269|PubMed:33206546}. Note=Co-localizes with POSTN in the Golgi. {ECO:0000250}.; [Isoform BMP1-3]: Secreted {ECO:0000269|PubMed:21453682}. |
| Mouse PG classification | NA |
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