| Gene Information | |
|---|---|
| Gene Name | PCLO |
| Organism | Homo sapiens (Human) |
| Gene Length | 5142 |
| Protein Names | Protein piccolo (Aczonin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000186472 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | PCLO |
| Uniprot ID | Q9Y6V0 |
| Pfam | PF00168; PF00595; PF05715 |
| In ASD | no |
| Allosteric Prediction | no (-0.268878359) |
| Ortholog in Animals | Alpaca_ PCLO ( ortholog_one2one ) GuineaPig_ PCLO ( ortholog_one2one ) Macaque_ PCLO ( ortholog_one2one ) Mouse_ Pclo ( ortholog_one2one ) Rat_ Pclo ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BSN |
| Tissue | cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Moderately expressed in the developing cerebral cortex. {ECO:0000269|PubMed:25832664}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UJD (NMR - ) |
| DBSNP | rs10261848 rs976714 |
| Subcellular location [CC] | Presynaptic active zone {ECO:0000250|UniProtKB:Q9QYX7}. Note=Colocalizes with BSN in developing axons. {ECO:0000250|UniProtKB:Q9JKS6}. |
| Mouse PG classification | LPG |
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