| Gene Information | |
|---|---|
| Gene Name | PCL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 567 |
| Protein Names | PHD finger protein 1 (Protein PHF1) (hPHF1) (Polycomb-like protein 1) (hPCl1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43189 |
| Gene Card | PHF1 |
| Uniprot ID | O43189 |
| Pfam | PF14061; PF00628; PF18104 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest levels in heart, skeletal muscle, and pancreas, lower levels in brain, placenta, lung, liver and kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E5P (NMR - ) 2M0O (NMR - ) 4HCZ (X-ray 1.85A ) 5XFN (X-ray 1.90A ) 5XFO (X-ray 1.90A ) 5XFP (X-ray 2.30A ) 6WAT (X-ray 1.80A ) 6WAV (X-ray 1.70A ) 7LKY (X-ray 1.85A ) |
| DBSNP | rs6934613 rs3116713 |
| Subcellular location [CC] | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes specifically to the promoters of numerous target genes. Localizes to double-strand breaks (DSBs) sites following DNA damage. Co-localizes with NEK6 in the centrosome. |
| Mouse PG classification | NA |
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