| Gene Information | |
|---|---|
| Gene Name | PCGF5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 256 |
| Protein Names | Polycomb group RING finger protein 5 (RING finger protein 159) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000180628 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86SE9 |
| Gene Card | PCGF5 |
| Uniprot ID | Q86SE9 |
| Pfam | PF16207 |
| In ASD | no |
| Allosteric Prediction | yes (0.02274794) |
| Ortholog in Animals | Alpaca_ PCGF5 ( ortholog_one2one ) Dog_ PCGF5 ( ortholog_one2one ) GuineaPig_ PCGF5 ( ortholog_one2one ) Macaque_ PCGF5 ( ortholog_one2one ) Mouse_ Pcgf5 ( ortholog_one2one ) Rat_ Pcgf5 ( ortholog_one2one ) Rabbit_ PCGF5 ( ortholog_one2one ) |
| Ohnologs | PCGF1, PCGF6, BMI1, PCGF3 |
| Paralogs | PCGF3, RNF2, PCGF6, BMI1, RING1, PCGF1, PCGF2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4S3O (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21282530, ECO:0000269|PubMed:25519132}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q3UK78}. Note=Recruited by the non-coding RNA Xist to specific nuclear foci that probably correspond to the inactivated X chromosome. {ECO:0000250|UniProtKB:Q3UK78}. |
| Mouse PG classification | NA |
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