| Gene Information | |
|---|---|
| Gene Name | SPCS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 169 |
| Protein Names | Signal peptidase complex subunit 1 (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000114902 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6A9 |
| Gene Card | SPCS1 |
| Uniprot ID | Q9Y6A9 |
| Pfam | PF06645 |
| In ASD | no |
| Allosteric Prediction | no (-0.806484067) |
| Ortholog in Animals | Alpaca_ SPCS1 ( ortholog_one2one ) Dog_ SPCS1 ( ortholog_one2one ) GuineaPig_ SPCS1 ( ortholog_one2one ) Macaque_ SPCS1 ( ortholog_one2one ) Mouse_ Spcs1 ( ortholog_one2one ) Rat_ Spcs1 ( ortholog_one2one ) Rabbit_ SPCS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7P2P (EM 4.90A ) 7P2Q (EM 4.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P83362}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P83362}. |
| Mouse PG classification | NA |
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