| Gene Information | |
|---|---|
| Gene Name | SPIN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 262 |
| Protein Names | Spindlin-1 (Ovarian cancer-related protein) (Spindlin1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000106723 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9Y657 |
| Gene Card | SPIN1 |
| Uniprot ID | Q9Y657 |
| Pfam | PF02513 |
| In ASD | no |
| Allosteric Prediction | no (-0.570857744) |
| Ortholog in Animals | Alpaca_ SPIN1 ( ortholog_one2one ) GuineaPig_ SPIN1 ( ortholog_one2one ) Macaque_ SPIN1 ( ortholog_one2one ) Mouse_ Spin1 ( ortholog_one2one ) Rat_ AABR07009715.1 ( ortholog_one2one ) Rabbit_ SPIN1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPIN4, SPIN2A, SPIN2B, SPIN3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in ovarian cancer tissues. {ECO:0000269|PubMed:22258766}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.007692(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2NS2 (X-ray 2.20A ) 4H75 (X-ray 2.10A ) 4MZF (X-ray 2.10A ) 4MZG (X-ray 1.70A ) 4MZH (X-ray 2.20A ) 5JSG (X-ray 2.50A ) 5JSJ (X-ray 2.35A ) 5Y5W (X-ray 3.30A ) 6I8B (X-ray 1.76A ) 6I8L (X-ray 1.58A ) 6I8Y (X-ray 1.52A ) 6QPL (X-ray 1.60A ) 7BQZ (X-ray 3.10A ) 7BU9 (X-ray 3.50A ) 7CNA (X-ray 1.60A ) 7E9M (X-ray 2.50A ) 7EA1 (X-ray 2.70A ) 7OCB (X-ray 1.42A ) |
| DBSNP | rs34794905 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16098913, ECO:0000269|PubMed:29061846}. Nucleus, nucleolus {ECO:0000269|PubMed:21960006}. |
| Mouse PG classification | NA |
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