| Gene Information | |
|---|---|
| Gene Name | PFN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 140 |
| Protein Names | Profilin-2 (Profilin II) |
| Target Name | profilin-2 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000070087 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P35080 |
| Gene Card | PFN2 |
| Uniprot ID | P35080 |
| Pfam | PF00235 |
| In ASD | no |
| Allosteric Prediction | no (-0.064232607) |
| Ortholog in Animals | Alpaca_ PFN2 ( ortholog_one2one ) GuineaPig_ PFN2 ( ortholog_one2one ) Mouse_ Pfn2 ( ortholog_one2one ) Rat_ Pfn2 ( ortholog_one2one ) Rabbit_ PFN2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PFN1, PFN3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.0125(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1D1J (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. |
| Mouse PG classification | NA |
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