| Gene Information | |
|---|---|
| Gene Name | PCDH18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1135 |
| Protein Names | Protocadherin-18 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000189184 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9HCL0 |
| Gene Card | PCDH18 |
| Uniprot ID | Q9HCL0 |
| Pfam | PF00028; PF08266 |
| In ASD | no |
| Allosteric Prediction | no (-1.234480434) |
| Ortholog in Animals | Alpaca_ PCDH18 ( ortholog_one2one ) Dog_ PCDH18 ( ortholog_one2one ) GuineaPig_ PCDH18 ( ortholog_one2one ) Macaque_ PCDH18 ( ortholog_one2one ) Mouse_ Pcdh18 ( ortholog_one2one ) Pig_ PCDH18 ( ortholog_one2one ) Rat_ Pcdh18 ( ortholog_one2one ) Rabbit_ PCDH18 ( ortholog_one2one ) |
| Ohnologs | PCDHB4, PCDHA6, PCDHGA2, PCDHB2, PCDHB3, PCDHB5, PCDHB6, PCDHB7, PCDHB15, PCDH12, PCDH17, PCDHB8, PCDHB10, PCDHB14, PCDHB12, PCDH8, PCDHB18P, PCDH19, PCDHB1, PCDHB13, PCDHB11, PCDHGA1, PCDHA9, PCDHA8, PCDHA7, PCDHA5, PCDHA4, PCDHA2, PCDHA1 |
| Paralogs | CDHR4, PCDHGB3, PCDHGB1, PCDHGA3, PCDH17, PCDHA13, PCDHGA8, PCDHB16, PCDHA11, PCDHGB6, PCDHGC5, PCDHGC4, PCDHB9, PCDHB10, PCDHA12, PCDHA10, PCDHA9, PCDHA7, PCDHA5, PCDH10, PCDHB6, PCDH15, PCDHB13, PCDHB2, PCDHGA7, PCDHGC3, PCDHB1, PCDHGA5, PCDHA3, PCDHAC2, PCDHB4, PCDHA4, PCDHB5, PCDHGA10, PCDHGB2, PCDH19, PCDH8, PCDHGA1, PCDHGA11, PCDHGA12, PCDHGA2, PCDHB7, PCDHGB7, PCDH12, PCDHGA9, PCDHGB4, PCDHGB5, PCDHA8, PCDHA6, PCDHA2, PCDHB12, PCDHB11, PCDHB14, PCDHB8, PCDHGA4, PCDHB15, CDH16, PCDHA1, PCDHB3, PCDHAC1, PCDHGA6 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues, with highest expression in lung and ovary. {ECO:0000269|PubMed:11549318}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 6VFR (X-ray 2.79A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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