| Gene Information | |
|---|---|
| Gene Name | PCDH10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1040 |
| Protein Names | Protocadherin-10 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000138650 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9P2E7 |
| Gene Card | PCDH10 |
| Uniprot ID | Q9P2E7 |
| Pfam | PF00028; PF08266; PF16492 |
| In ASD | no |
| Allosteric Prediction | no (-0.291315652) |
| Ortholog in Animals | Alpaca_ PCDH10 ( ortholog_one2one ) Dog_ PCDH10 ( ortholog_one2one ) GuineaPig_ PCDH10 ( ortholog_one2one ) Macaque_ PCDH10 ( ortholog_one2one ) Mouse_ Pcdh10 ( ortholog_one2one ) Pig_ PCDH10 ( ortholog_one2one ) Rat_ Pcdh10 ( ortholog_one2one ) Rabbit_ PCDH10 ( ortholog_one2one ) |
| Ohnologs | PCDHB4, PCDHA6, PCDHGA2, PCDHB2, PCDHB3, PCDHB5, PCDHB6, PCDHB7, PCDHB15, PCDH12, PCDH17, PCDHB8, PCDHB10, PCDHB14, PCDHB12, PCDH8, PCDHB18P, PCDH19, PCDHB1, PCDHB13, PCDHB11, PCDHGA1, PCDHA9, PCDHA8, PCDHA7, PCDHA5, PCDHA4, PCDHA2, PCDHA1 |
| Paralogs | CDHR4, PCDHGB3, PCDHGB1, PCDHGA3, PCDH17, PCDHA13, PCDHGA8, PCDHB16, PCDHA11, PCDHGB6, PCDHGC5, PCDHGC4, PCDHB9, PCDHB10, PCDHA12, PCDHA10, PCDHA9, PCDHA7, PCDHA5, PCDHB6, PCDH15, PCDHB13, PCDHB2, PCDHGA7, PCDHGC3, PCDHB1, PCDHGA5, PCDHA3, PCDHAC2, PCDHB4, PCDHA4, PCDHB5, PCDHGA10, PCDHGB2, PCDH19, PCDH8, PCDH18, PCDHGA1, PCDHGA11, PCDHGA12, PCDHGA2, PCDHB7, PCDHGB7, PCDH12, PCDHGA9, PCDHGB4, PCDHGB5, PCDHA8, PCDHA6, PCDHA2, PCDHB12, PCDHB11, PCDHB14, PCDHB8, PCDHGA4, PCDHB15, CDH16, PCDHA1, PCDHB3, PCDHAC1, PCDHGA6 |
| Tissue | brain, placenta, cerebral.cortex |
| Tissue Specificity | Moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tissues tested. {ECO:0000269|PubMed:11549318}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 6VFQ (X-ray 2.30A ) 6VFW (X-ray 3.60A ) 6VG4 (X-ray 3.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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