| Gene Information | |
|---|---|
| Gene Name | PCDH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1060 |
| Protein Names | Protocadherin-1 (Cadherin-like protein 1) (Protocadherin-42) (PC42) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000156453 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q08174 |
| Gene Card | PCDH1 |
| Uniprot ID | Q08174 |
| Pfam | PF00028; PF08266; PF08374 |
| In ASD | no |
| Allosteric Prediction | no (-0.787302305) |
| Ortholog in Animals | Alpaca_ PCDH1 ( ortholog_one2one ) Dog_ PCDH1 ( ortholog_one2one ) GuineaPig_ PCDH1 ( ortholog_one2one ) Macaque_ PCDH1 ( ortholog_one2one ) Mouse_ Pcdh1 ( ortholog_one2one ) Pig_ PCDH1 ( ortholog_one2one ) Rat_ Pcdh1 ( ortholog_one2one ) Rabbit_ PCDH1 ( ortholog_one2one ) |
| Ohnologs | PCDH11X, PCDH9, PCDH7 |
| Paralogs | CDH7, CDH9, CDH20, CDH4, CDH18, PCDH20, CDH26, CDH19, PCDH9, CDH3, PCDH11Y, PCDH11X, CDH17, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, CDHR1, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH13, CDH6, CDH1, CDHR2, CDH22, CDH5, CDH2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the brain and neuro-glial cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6BX7 (X-ray 2.85A ) 6MGA (X-ray 3.15A ) 6PIM (X-ray 3.05A ) 6VFP (X-ray 3.20A ) |
| DBSNP | rs12517385 rs12515587 rs3822357 |
| Subcellular location [CC] | Cell junction. Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. |
| Mouse PG classification | NA |
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