| Gene Information | |
|---|---|
| Gene Name | PCMT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 227 |
| Protein Names | Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) |
| Target Name | protein-l-isoaspartate(d-aspartate) o-methyltransferase |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000120265 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P22061 |
| Gene Card | PCMT1 |
| Uniprot ID | P22061 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.111408089) |
| Ortholog in Animals | Alpaca_ PCMT1 ( ortholog_one2one ) Dog_ PCMT1 ( ortholog_one2one ) GuineaPig_ PCMT1 ( ortholog_one2one ) Macaque_ PCMT1 ( ortholog_one2one ) Mouse_ Pcmt1 ( ortholog_one2one ) Pig_ PCMT1 ( ortholog_one2one ) Rat_ Pcmt1 ( ortholog_one2one ) Rabbit_ PCMT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PCMTD1, PCMTD2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1I1N (X-ray 1.50A ) 1KR5 (X-ray 2.10A ) |
| DBSNP | rs4816 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:3167043}. |
| Mouse PG classification | NA |
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