| Gene Information | |
|---|---|
| Gene Name | PCCA |
| Organism | Homo sapiens (Human) |
| Gene Length | 728 |
| Protein Names | Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha) |
| Target Name | propionyl-coa carboxylase alpha chain, mitochondrial |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000175198 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P05165 |
| Gene Card | PCCA |
| Uniprot ID | P05165 |
| Pfam | PF02785; PF00289; PF00364; PF02786; PF18140 |
| In ASD | no |
| Allosteric Prediction | yes (0.214179766) |
| Ortholog in Animals | Alpaca_ PCCA ( ortholog_one2one ) Dog_ PCCA ( ortholog_one2one ) GuineaPig_ PCCA ( ortholog_one2one ) Macaque_ PCCA ( ortholog_one2one ) Mouse_ Pcca ( ortholog_one2one ) Pig_ PCCA ( ortholog_one2one ) Rat_ Pcca ( ortholog_one2one ) Rabbit_ PCCA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MCCC1, ACACA, ACACB, PC |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.017880(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CQY (NMR - ) 2JKU (X-ray 1.50A ) |
| DBSNP | rs794727479 rs141371306 rs202247814 rs202247815 rs375628794 rs121964958 rs794727087 rs1301904623 rs1443858896 rs35719359 rs61749895 rs118169528 rs796052018 rs771438170 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:10101253, ECO:0000269|PubMed:16023992}. |
| Mouse PG classification | NA |
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