| Gene Information | |
|---|---|
| Gene Name | CASP12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 341 |
| Protein Names | Inactive caspase-12 (CASP-12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000204403 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6UXS9 |
| Gene Card | CASP12 |
| Uniprot ID | Q6UXS9 |
| Pfam | PF00619 |
| In ASD | no |
| Allosteric Prediction | no (-0.769345454) |
| Ortholog in Animals | Alpaca_ CASP12 ( ortholog_one2one ) Dog_ CASP12 ( ortholog_one2one ) GuineaPig_ CASP12 ( ortholog_one2one ) Macaque_ CASP12 ( ortholog_one2one ) Mouse_ Casp12 ( ortholog_one2one ) Rat_ Casp12 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PYCARD, CASP14, CASP8, CASP2, CASP6, CFLAR, CASP10, CARD18, CASP9, CASP1, CARD16, CASP5, CASP4, CASP3, CASP7, PYDC1 |
| Tissue | NA |
| Tissue Specificity | Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis. {ECO:0000269|PubMed:12054529}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs693001 rs497116 rs647039 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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