| Gene Information | |
|---|---|
| Gene Name | PC8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 785 |
| Protein Names | Proprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q16549 |
| Gene Card | PCSK7 |
| Uniprot ID | Q16549 |
| Pfam | PF01483; PF00082; PF16470 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs608620 rs45539233 rs45574931 rs473131 rs473093 |
| Subcellular location [CC] | Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Seems to be localized intracellularly to the trans Golgi network. {ECO:0000250}. |
| Mouse PG classification | NA |
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