Gene Information
Gene NamePC7
OrganismHomo sapiens (Human)
Gene Length785
Protein NamesProprotein convertase subtilisin/kexin type 7 (EC 3.4.21.-) (Lymphoma proprotein convertase) (Prohormone convertase 7) (Proprotein convertase 7) (PC7) (Proprotein convertase 8) (PC8) (hPC8) (Subtilisin/kexin-like protease PC7)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ16549
Gene CardPCSK7
Uniprot IDQ16549
PfamPF01483; PF00082; PF16470
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs608620  rs45539233  rs45574931  rs473131  rs473093 
Subcellular location [CC]Golgi apparatus, trans-Golgi network membrane {ECO:0000250};
Single-pass type I membrane protein {ECO:0000250}. Note=Seems to be localized intracellularly to the trans Golgi network. {ECO:0000250}.
Mouse PG classificationNA
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