| Gene Information | |
|---|---|
| Gene Name | PC |
| Organism | Homo sapiens (Human) |
| Gene Length | 1178 |
| Protein Names | Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) |
| Target Name | pyruvate carboxylase, mitochondrial |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000173599 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P11498 |
| Gene Card | PC |
| Uniprot ID | P11498 |
| Pfam | PF02785; PF00289; PF00364; PF02786; PF00682; PF02436 |
| In ASD | no |
| Allosteric Prediction | yes (1.272132785) |
| Ortholog in Animals | Alpaca_ PC ( ortholog_one2one ) Dog_ PC ( ortholog_one2one ) GuineaPig_ PC ( ortholog_one2one ) Macaque_ PC ( ortholog_one2one ) Mouse_ Pcx ( ortholog_one2one ) Pig_ PC ( ortholog_one2one ) Rat_ Pc ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MCCC1, ACACA, PCCA, ACACB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3BG3 (X-ray 2.80A ) 3BG9 (X-ray 3.00A ) |
| DBSNP | rs7104156 rs28940591 rs119103241 rs1258494752 rs113994143 rs119103242 rs28940589 rs113994145 rs28940590 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:9585002}. |
| Mouse PG classification | LPG |
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