| Gene Information | |
|---|---|
| Gene Name | PIP4P1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 277 |
| Protein Names | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 1 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase I) (Transmembrane protein 55B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000165782 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86T03 |
| Gene Card | PIP4P1 |
| Uniprot ID | Q86T03 |
| Pfam | PF09788 |
| In ASD | no |
| Allosteric Prediction | no (-1.22770667) |
| Ortholog in Animals | Alpaca_ PIP4P1 ( ortholog_one2one ) Dog_ PIP4P1 ( ortholog_one2one ) GuineaPig_ PIP4P1 ( ortholog_one2one ) Macaque_ PIP4P1 ( ortholog_one2one ) Mouse_ Pip4p1 ( ortholog_one2one ) Pig_ PIP4P1 ( ortholog_one2one ) Rat_ Pip4p1 ( ortholog_one2one ) |
| Ohnologs | PIP4P2 |
| Paralogs | PIP4P2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:16365287}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Late endosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250|UniProtKB:Q3TWL2}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q3TWL2}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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