| Gene Information | |
|---|---|
| Gene Name | STK39 |
| Organism | Homo sapiens (Human) |
| Gene Length | 545 |
| Protein Names | STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39) |
| Target Name | ste20/sps1-related proline-alanine-rich protein kinase |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000198648 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UEW8 |
| Gene Card | STK39 |
| Uniprot ID | Q9UEW8 |
| Pfam | PF12202; PF00069 |
| In ASD | yes |
| Allosteric Prediction | yes (1.023269401) |
| Ortholog in Animals | Alpaca_ STK39 ( ortholog_one2one ) Dog_ STK39 ( ortholog_one2one ) GuineaPig_ STK39 ( ortholog_one2one ) Macaque_ STK39 ( ortholog_one2one ) Mouse_ Stk39 ( ortholog_one2one ) Pig_ STK39 ( ortholog_one2one ) Rat_ Stk39 ( ortholog_one2one ) Rabbit_ STK39 ( ortholog_one2one ) |
| Ohnologs | OXSR1 |
| Paralogs | PAK5, PAK6, PAK4, SBK2, MAP4K1, PAK2, PAK1, PAK3, MINK1, TNIK, MAP4K5, SLK, MAP3K14, MAP3K19, STRADB, STK4, MAP3K1, TAOK2, MAP4K3, NRK, STRADA, MAP2K3, STK10, MAP2K6, STK26, TAOK3, TAOK1, MAP3K8, MAP4K2, OXSR1, STK3, NEK4, STK25, STK24, MAP4K4 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.073684(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 7O86 (X-ray 1.73A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. Note=Nucleus when caspase-cleaved. {ECO:0000305}. |
| Mouse PG classification | NA |
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