| Gene Information | |
|---|---|
| Gene Name | GADD45A |
| Organism | Homo sapiens (Human) |
| Gene Length | 165 |
| Protein Names | Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage-inducible transcript 1 protein) (DDIT-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000116717 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P24522 |
| Gene Card | GADD45A |
| Uniprot ID | P24522 |
| Pfam | PF01248 |
| In ASD | no |
| Allosteric Prediction | yes (0.282456129) |
| Ortholog in Animals | Alpaca_ GADD45A ( ortholog_one2one ) Dog_ GADD45A ( ortholog_one2one ) GuineaPig_ GADD45A ( ortholog_one2one ) Macaque_ GADD45A ( ortholog_one2one ) Mouse_ Gadd45a ( ortholog_one2one ) Pig_ GADD45A ( ortholog_one2one ) Rat_ Gadd45a ( ortholog_one2one ) Rabbit_ GADD45A ( ortholog_one2one ) |
| Ohnologs | GADD45G |
| Paralogs | GADD45G, GADD45B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.075(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KG4 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:7973727}. |
| Mouse PG classification | NA |
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