| Gene Information | |
|---|---|
| Gene Name | PAXIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1069 |
| Protein Names | PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000157212 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6ZW49 |
| Gene Card | PAXIP1 |
| Uniprot ID | Q6ZW49 |
| Pfam | PF00533; PF12738; PF16770 |
| In ASD | no |
| Allosteric Prediction | yes (0.105868746) |
| Ortholog in Animals | Alpaca_ PAXIP1 ( ortholog_one2many ) Dog_ PAXIP1 ( ortholog_one2one ) GuineaPig_ PAXIP1 ( ortholog_one2one ) Macaque_ PAXIP1 ( ortholog_one2one ) Mouse_ Paxip1 ( ortholog_one2one ) Pig_ PAXIP1 ( ortholog_one2one ) Rat_ Paxip1 ( ortholog_one2one ) Rabbit_ PAXIP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MDC1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.110532(Rat);0.064600(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3SQD (X-ray 2.15A ) |
| DBSNP | rs3501 |
| Subcellular location [CC] | Nucleus matrix {ECO:0000250|UniProtKB:Q6NZQ4}. Chromosome {ECO:0000269|PubMed:15456759, ECO:0000269|PubMed:17690115}. Note=Localizes to DNA damage foci upon ionizing radiation. {ECO:0000269|PubMed:15456759, ECO:0000269|PubMed:17690115}. |
| Mouse PG classification | NA |
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