| Gene Information | |
|---|---|
| Gene Name | PAX5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 391 |
| Protein Names | Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000196092 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q02548 |
| Gene Card | PAX5 |
| Uniprot ID | Q02548 |
| Pfam | PF00292; PF12403 |
| In ASD | no |
| Allosteric Prediction | no (-0.261689973) |
| Ortholog in Animals | Alpaca_ PAX5 ( ortholog_one2one ) Dog_ PAX5 ( ortholog_one2one ) GuineaPig_ PAX5 ( ortholog_one2one ) Macaque_ PAX5 ( ortholog_one2one ) Mouse_ Pax5 ( ortholog_one2one ) Pig_ PAX5 ( ortholog_one2one ) Rat_ Pax5 ( ortholog_one2one ) Rabbit_ PAX5 ( ortholog_one2one ) |
| Ohnologs | PAX2, PAX8 |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | lymph.node, appendix, spleen, tonsil, brain |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1K78 (X-ray 2.25A ) 1MDM (X-ray 2.80A ) |
| DBSNP | rs868494257 rs926053251 rs115889954 rs398123063 rs137870876 rs372989600 rs34810717 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:31941781}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |