| Gene Information | |
|---|---|
| Gene Name | PAX3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 479 |
| Protein Names | Paired box protein Pax-3 (HuP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000135903 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P23760 |
| Gene Card | PAX3 |
| Uniprot ID | P23760 |
| Pfam | PF00046; PF00292; PF12360 |
| In ASD | no |
| Allosteric Prediction | no (-0.656502641) |
| Ortholog in Animals | Alpaca_ PAX3 ( ortholog_one2one ) Dog_ PAX3 ( ortholog_one2one ) GuineaPig_ PAX3 ( ortholog_one2one ) Macaque_ PAX3 ( ortholog_one2one ) Mouse_ Pax3 ( ortholog_one2one ) Pig_ PAX3 ( ortholog_one2one ) Rat_ Pax3 ( ortholog_one2one ) Rabbit_ PAX3 ( ortholog_one2one ) |
| Ohnologs | PAX7 |
| Paralogs | ARGFX, PAX7, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3CMY (X-ray 1.95A ) |
| DBSNP | rs104893653 rs104893652 rs1419548558 rs104893650 rs267606931 rs1553593928 rs387906947 rs587776586 rs104893651 rs104893654 rs1189463428 rs1228590199 rs1380858784 rs774528745 rs1020175890 rs2234675 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21965087}. |
| Mouse PG classification | NA |
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