| Gene Information | |
|---|---|
| Gene Name | PAX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 417 |
| Protein Names | Paired box protein Pax-2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000075891 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q02962 |
| Gene Card | PAX2 |
| Uniprot ID | Q02962 |
| Pfam | PF00292; PF12403 |
| In ASD | no |
| Allosteric Prediction | no (-0.529477121) |
| Ortholog in Animals | Alpaca_ PAX2 ( ortholog_one2one ) Dog_ PAX2 ( ortholog_one2one ) GuineaPig_ PAX2 ( ortholog_one2one ) Macaque_ PAX2 ( ortholog_one2one ) Mouse_ Pax2 ( ortholog_one2one ) Pig_ PAX2 ( ortholog_one2one ) Rat_ Pax2 ( ortholog_one2one ) Rabbit_ PAX2 ( ortholog_one2one ) |
| Ohnologs | PAX8, PAX5 |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | kidney, cortex.of.kidney |
| Tissue Specificity | Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs201239919 rs587777708 rs104894170 rs79555199 rs1554856032 rs773306707 rs1201078720 rs201383632 rs370214925 rs1131692055 rs1403345811 rs893370744 rs78738655 rs138490772 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | HPG |
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