| Gene Information | |
|---|---|
| Gene Name | PATL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 770 |
| Protein Names | Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) (hPat1b) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000166889 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q86TB9 |
| Gene Card | PATL1 |
| Uniprot ID | Q86TB9 |
| Pfam | PF09770 |
| In ASD | no |
| Allosteric Prediction | no (-1.469508297) |
| Ortholog in Animals | Alpaca_ PATL1 ( ortholog_one2one ) Dog_ PATL1 ( ortholog_one2one ) GuineaPig_ PATL1 ( ortholog_one2one ) Macaque_ PATL1 ( ortholog_one2one ) Mouse_ Patl1 ( ortholog_one2one ) Pig_ PATL1 ( ortholog_one2one ) Rat_ Patl1 ( ortholog_one2one ) Rabbit_ PATL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PATL2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:17936923}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.062548(Mouse);0.002714(Rat);0.053846(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2XEQ (X-ray 3.10A ) 2XER (X-ray 2.95A ) 2XES (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, P-body {ECO:0000269|PubMed:17936923, ECO:0000269|PubMed:20543818, ECO:0000269|PubMed:20584987, ECO:0000269|PubMed:20826699, ECO:0000269|PubMed:20852261, ECO:0000269|PubMed:22090346, ECO:0000269|PubMed:32354837}. Nucleus {ECO:0000269|PubMed:22090346}. Nucleus, PML body {ECO:0000269|PubMed:22090346}. Nucleus speckle {ECO:0000269|PubMed:22090346}. Note=Predominantly cytoplasmic (PubMed:22090346). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner (PubMed:22090346). Enriched in splicing speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus (PubMed:22090346). {ECO:0000269|PubMed:22090346}. |
| Mouse PG classification | NA |
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