| Gene Information | |
|---|---|
| Gene Name | PPRC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1664 |
| Protein Names | Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PGC-1-related coactivator) (PRC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000148840 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5VV67 |
| Gene Card | PPRC1 |
| Uniprot ID | Q5VV67 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-1.263696156) |
| Ortholog in Animals | Alpaca_ PPRC1 ( ortholog_one2one ) Dog_ PPRC1 ( ortholog_one2one ) GuineaPig_ PPRC1 ( ortholog_one2one ) Macaque_ PPRC1 ( ortholog_one2one ) Mouse_ Pprc1 ( ortholog_one2one ) Pig_ PPRC1 ( ortholog_one2one ) Rat_ Pprc1 ( ortholog_one2one ) Rabbit_ PPRC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPARGC1B, PPARGC1A |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in heart and skeletal muscle, moderately in lung, placenta, intestine, liver, kidney, spleen, thymus, colon and brain. Also expressed in several oncocytic thyroid tumors. {ECO:0000269|PubMed:11340167, ECO:0000269|PubMed:14550271}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17114388 rs17855877 rs118161359 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11340167}. Note=Colocalizes with NRF1. {ECO:0000250}. |
| Mouse PG classification | NA |
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