| Gene Information | |
|---|---|
| Gene Name | SHP |
| Organism | Homo sapiens (Human) |
| Gene Length | 257 |
| Protein Names | Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15466 |
| Gene Card | NR0B2 |
| Uniprot ID | Q15466 |
| Pfam | PF00104 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Liver. Low levels of expression were detected in heart and pancreas. {ECO:0000269|PubMed:8650544}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001942(Rat);0.028571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1YUC (X-ray 1.90A ) 2Q3Y (X-ray 2.40A ) 2Z4J (X-ray 2.60A ) 4DOR (X-ray 1.90A ) 4ONI (X-ray 1.80A ) 5UFS (X-ray 2.12A ) 6W9M (X-ray 1.59A ) |
| DBSNP | rs777291973 rs6659176 rs202154574 rs74315350 rs199976415 rs200475847 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14752053, ECO:0000269|PubMed:28797635}. Cytoplasm {ECO:0000269|PubMed:14752053}. Note=Colocalizes with NEUROD1 in the nucleus. |
| Mouse PG classification | NA |
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