| Gene Information | |
|---|---|
| Gene Name | LARP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1096 |
| Protein Names | La-related protein 1 (La ribonucleoprotein domain family member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000155506 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6PKG0 |
| Gene Card | LARP1 |
| Uniprot ID | Q6PKG0 |
| Pfam | PF05383 |
| In ASD | no |
| Allosteric Prediction | no (-0.431751432) |
| Ortholog in Animals | Alpaca_ LARP1 ( ortholog_one2one ) Dog_ LARP1 ( ortholog_one2one ) GuineaPig_ LARP1 ( ortholog_one2one ) Macaque_ LARP1 ( ortholog_one2one ) Mouse_ Larp1 ( ortholog_one2one ) Pig_ LARP1 ( ortholog_one2one ) Rat_ Larp1 ( ortholog_one2one ) Rabbit_ LARP1 ( ortholog_one2one ) |
| Ohnologs | LARP1B |
| Paralogs | LARP4, SSB, LARP4B, LARP7, LARP1B, LARP6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4ZC4 (X-ray 1.86A ) 5C0V (X-ray 2.20A ) 5V4R (X-ray 1.77A ) 5V7C (X-ray 2.59A ) 5V87 (X-ray 1.69A ) 6PW3 (X-ray 2.34A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20430826, ECO:0000269|PubMed:24532714, ECO:0000269|PubMed:28650797}. Cytoplasmic granule {ECO:0000269|PubMed:24532714, ECO:0000269|PubMed:25940091}. Note=Colocalizes with RPTOR and PABPC1 in cytoplasmic granules that resemble stress granules. {ECO:0000269|PubMed:24532714, ECO:0000269|PubMed:25940091}. |
| Mouse PG classification | NA |
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