| Gene Information | |
|---|---|
| Gene Name | RNF141 |
| Organism | Homo sapiens (Human) |
| Gene Length | 230 |
| Protein Names | RING finger protein 141 (Zinc finger protein 230) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000110315 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WVD5 |
| Gene Card | RNF141 |
| Uniprot ID | Q8WVD5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.390459185) |
| Ortholog in Animals | Alpaca_ RNF141 ( ortholog_one2one ) Dog_ RNF141 ( ortholog_one2one ) GuineaPig_ RNF141 ( ortholog_one2one ) Macaque_ RNF141 ( ortholog_one2one ) Mouse_ Rnf141 ( ortholog_one2one ) Pig_ RNF141 ( ortholog_one2one ) Rat_ rnf141 ( ortholog_one2one ) Rabbit_ RNF141 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients. {ECO:0000269|PubMed:11672448}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ECN (NMR - ) 5XEK (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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