| Gene Information | |
|---|---|
| Gene Name | PARD6B |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000124171 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BYG5 |
| Gene Card | PARD6B |
| Uniprot ID | Q9BYG5 |
| Pfam | PF00564; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.969173327) |
| Ortholog in Animals | Alpaca_ PARD6B ( ortholog_one2one ) Dog_ PARD6B ( ortholog_one2one ) GuineaPig_ PARD6B ( ortholog_one2one ) Macaque_ PARD6B ( ortholog_one2one ) Mouse_ Pard6b ( ortholog_one2one ) Pig_ PARD6B ( ortholog_one2one ) Rat_ Pard6b ( ortholog_one2one ) Rabbit_ PARD6B ( ortholog_one2one ) |
| Ohnologs | PARD6A, PARD6G |
| Paralogs | PARD6A, PARD6G |
| Tissue | NA |
| Tissue Specificity | Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.023983(Mouse);0.138248(Rat);0.120593(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. |
| Mouse PG classification | NA |
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